WHAT IS DEPRESSION?Depression is a common and serious medical illness that causes feelings of sadness. It can lead to a variety of emotional and physical problems and can decrease your ability to function at work and at home. |
![]() |
Symptoms of depression include fatigue, anxiety, irritability, restlessness, loss of enjoyment, appetite changes, changes in sleep patterns, and thoughts of suicide. Almost 7% of the population experiences at least one major depressive episode in their life. It’s more common in women than men.
Science abstracts on Depression
- Endocannabinoid system dysfunction in mood and related disorders
- Antidepressant-like and anxiolytic-like effects of CBD
- The endocannabinoid system and the treatment of mood and anxiety disorders
- Endocannabinoid signaling in the etiology and treatment of major depressive illness
- Antidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors
- >Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants
- Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa
- Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
- Serum contents of endocannabinoids are correlated with blood pressure in depressed women
- The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants
- Antidepressants and changes in concentration of endocannabinoids and n-acylethanolamines in rat brain structures
- Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors
- Prohedonic effect of CBD in a rat model of depression
- Antidepressant-like and anxiolytic-like effects of CBD